One issue that can create a difference in the General ledger column when doing a bank reconciliation is if the accounts payable person accidentally put a invoice to the check register.
This issue will present as a difference in the running balance of the bank account and the General Ledger balance showing in the top right corner of the bank account.
To compare the two, while in the bank account press "V" for view on your keyboard then "B" for running balance. These are hot keys and can also be accessed by selecting the F6 option once in the bank account.
If the running balance at the bottom of the bank account is different from the amount shown it could be due to a payable.
To find this go into A-Accounting D-Chart of Accounts then highlight the bank account in question. Once it is highlighted use the F8 option to look at the detail of the account.
To quickly see if there is an incorrect posting either press "G" or the Group options. This will put the transactions together by type. By scrolling or using the F8 option to make sure that there are only A-Adjustments, C- Checks and D- Deposit type transactions. If there is a P-Payable this needs to be corrected and removed from the bank account.
To correct the payable all that needs to be done is highlight on the selection then f4 to edit. This will open the record and from there the correct account can be selected and it will move it out of the bank account.
http://help.pluss.co/HELP/PTM%20Vision%20Help/default.aspx?pageid=scheduling#pageid=reconciling_checks_